Pluto Bioinformatics

GSE130229 (mouse): EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells (RNA-Seq)

Bulk RNA sequencing

We identified a novel cofactor of PRC2, expressed predominantly in the gonad, that limits PRC2 enzymatic activity by impeding the interaction between the core complex and the accessory subunits. SOURCE: Nicolas Servant (Nicolas.Servant@curie.fr) - Institut Curie