To identify the biological pathways underlying impaired differentiation of Parp3-deficient NPSC to astrocytes, RNAseq of the Parp3+/+ and Parp3-/- astrocytes were performed 4 days upon differentiation. Briefly, NPSC were isolated from the forebrains of Parp3+/+ and Parp3-/- 8-day-old mice. Viable single cells were induced to differentiate into astrocytes for 4 days and samples were collected for total RNA isolation and RNA sequencing. SOURCE: Françoise DANTZER (francoise.dantzer@unistra.fr) - Biotechnology and Cell Signaling CNRS

Pluto Bioinformatics

GSE138807: Comparative RNAseq of Mouse Parp3+/+ and Parp3-/- Neural Stem Progenitor Cells (NPSC)