Pluto Bioinformatics

GSE138769: RNA sequencing of whole Dorsal Root Ganglia (DRG) upon Environmental Enrichment and Sciatic Nerve Axotomy (EE_SNA) or Sciatic Nerve Axotomy alone (SH_SNA) compared to Standard Housing Sham (SH_Sham)

Bulk RNA sequencing

Purpose: compare the gene expression in whole DRG of mice: A) undergone to nerve axotomy vs control condition B) pre-exposed to EE and undergone to nerve axotomy vs control condition; Results: we found that EE_SNA induces transcriptional changes strongly promoting axon regeneration. We call this "Enriched Conditioning" SOURCE: Matt,C,Danzi ( - University of Miami

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