Pluto Bioinformatics

GSE130110: CD8+ T Cells Promote Maturation of Liver-Resident NK Cells via the CD70-CD27 axis

Bulk RNA sequencing

We discovered that LrNK cells exhibit a relatively immature phenotype and impaired cytotoxic capacity in the absence of CD8+ T cells. The provision of CD8+ T cells to Cd8-/- or Rag1-/- mice led to the restoration of LrNK cell maturation SOURCE: Xiaolei Hao Institute of Immunology, USTC