Pluto Bioinformatics

GSE114927: RNAseq analysis of whole islets from pre-weaning wild type and Akita mice

Bulk RNA sequencing

This study aims to determine the effects of proinsulin misfolding/ER stress on -cell dynamics and function in Akita mice. The RNAseq experiment offers the opportunity to investigate the impact of proinsulin misfolding/ ER stress on the genetic signature of islets isolated during the neonatal period in the Akita mice preceding the development of hyperglycemia. SOURCE: Yael Riahi (yael.riahi@mail.huji.ac.il) - Hadassah Medical Center