Pluto Bioinformatics

GSE61851: RNA-seq analysis of withdrawal of miR-155 hyperexpression in miR-155-addicted tumors

Bulk RNA sequencing

Overexpression of miR-155 in hematological tissue leads to the onset of lymphoma, and Tet-off shutdown of this overexpression reverses the disease phenotype in mir-155LSLtTA mice. This study compares the gene expression profiles of tumors with miR-155 overexpression and withdrawal. SOURCE: Christopher,J,Cheng (christopher.cheng@yale.edu) - Yale University