Pluto Bioinformatics

GSE139506: Acute Kidney Injury Transcriptional Profiles:Single Cell RNA Sequencing reveals Injury induced Renal Developmental programreactivation and Lineage Infidelity in adult kidney

Bulk RNA sequencing

Acute Kidney Injury (AKI) is a rapid renal function decline associated with pronounced morbidity and mortality.Single Cell RNA Sequencing is a powerful tool allowing for examiningtranscriptional changes in multiple renal cell populations involved in the injury response. Our study reveals renal developmental gene re-activation and lineage infidelity in response to ischemia/reperfusioninduced AKI, along with the novel genes which might serve as markers of acute kidney disease SOURCE: Steve Potter Cincinnati Children's Hospital Research Foundation