Pluto Bioinformatics

GSE60691: Disrupting SUMOylation potentiates transactivation function and ameliorates polyglutamine AR-mediated disease

Bulk RNA sequencing

Our findings demonstrate beneficial effects of enhancing transactivation function of the ligand-activated polyQ AR and indicate that the SUMOylation pathway may provide new targets for therapeutic intervention. SOURCE: Richard,C,McEachin (mceachin@umich.edu) - University of Michigan