Pluto Bioinformatics

GSE99596: SIRT7 Antagonizes TGF- Signaling and Inhibits Breast Cancer Metastasis

Bulk RNA sequencing

Protein deacetylase SIRT7 is significantly downregulated in lung metastases of human patient and mouse tissues, and predicted metastasis-free survival. To explore the roles of SIRT7 in breast cancer, we analysed the gene expressions in breast cancer BT549 cells with SIRT7 knockdown or not. SOURCE: Xiaolong Tang (terrytang15szu@163.com) - shenzhen university