Pluto Bioinformatics

GSE131568: Differential expression of circular RNA in oral leukoplakia: novel potential biomarkers exploration for diagnosis and prognosis of precancer

Bulk RNA sequencing

6 pairs of OLK tissues and normal oral mucusal (NOM) tissues were obtained to detect circRNAs expression.The profile data showed that 366 circRNAs were significantly dysregulated in the OLK tissues, including 65 upregulated and 301 downregulated circRNA transcripts.There are 28 circRNAs were discovered firstly. 7 out of 10 selected circRNAs were further validated using Qrt-PCR SOURCE: Zhou haiwen (haiwen39@126.com) - Shanghai Key Laboratory of Stomatology ＆ Shanghai Research Institute of Stomatology Shanghai Ninth People’s Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine