Pluto Bioinformatics

GSE157518 (mouse): VISTA re-programs macrophage biology through the combined regulation of tolerance and anti-inflammatory pathways

Bulk RNA sequencing

1) BMDMs treated with anti-VISTA under tolerizing and immunizing conditions. 2) Time course analysis of anti-VISTA-induced alterations in human monocytes after anti-VISTA treatment. 3) Time course analysis of anti-VISTA-induced alterations in BMDMs after anti-VISTA treatment. 4) Single cell ATAC-seq of BMDMs tolerized in the presence or IgG or anti-VISTA. SOURCE: Evelien Schaafsma Dartmouth