We report the mRNA profile of aged mice (24 months old) fed either a control diet or a diet containing Rapamycin (14 ppm) for 3 months. After drug treatement, the hearts of the mice were removed and total mRNA was removed from the tissue. Analysis revealed that there were 700 significantly differentially expressed genes between the control fed group and the Rapamycin diet group by our analysis. SOURCE: Simon Melov (smelov@buckinstitute.org) - Melov Lab Buck Institute for Research on Aging

Pluto Bioinformatics

GSE48043: Late life rapamycin treatment reverses age-related heart dysfunction