Pluto Bioinformatics

GSE77646: Gene expression profiling of AR deletion in prostate luminal cells

Bulk RNA sequencing

Benign prostatic hyperplasia (BPH) is a common urological disease that adversely affects quality of life among elderly males, but its etiology remains poorly understood. We show that the expression of the androgen receptor (AR) is decreased in the luminal epithelial cells of human BPH specimens and is inversely correlated with the degree of regional prostatic inflammation. SOURCE: Chad Creighton (creighto@bcm.tmc.edu) - Baylor College of Medicine