Pluto Bioinformatics

GSE69735: Recurrent alterations of TNFAIP3 (A20) in T-cell large granular lymphocytic leukemia

Bulk RNA sequencing

We identified a novel recurrent genetic lesion in T-LGL. Mutations of the tumour suppressor gene TNFAIP3 causing amino-acid exchanges or protein truncations were seen in 3/39 cases (8%). SOURCE: Ludger Klein-Hitpass (ludger.klein-hitpass@uni-essen.de) - BioChip Lab Institut fuer Zellbiologie