Pluto Bioinformatics

GSE143790: Gene expression in DCIS.COM with BCL9 knockdown

Bulk RNA sequencing

There is limited research on which specific Wnt targets are regulated by B-Cell Lymphoma-9 (BCL9) and whether BCL9 regulates other signaling pathways to drive cancer malignancy. Here we demonstrated that BCL9 drives DCIS invasive progression by regulation of genes involved in cellular growth, invasion and migration. SOURCE: Hanan Elsarraj (helsarraj@kumc.edu) - Fariba Behbod University of Kansas Medical Center