Pluto Bioinformatics

GSE63647: Macrophage Gene Expression Upon Infection with Anaplasma phagocytophilum in the Presence and Absence of the Tick Salivary Protein SL2

Bulk RNA sequencing

Previously, we observed that a tick salivary protein named sialostatin L2 (SL2) mitigates caspase 1-mediated inflammation upon Anaplasma phagocytophilum infection. Here we are performing next-generation sequencing to determine the global effect of SL2 upon A. phagocytophilum infection of macrophages. SOURCE: Amol,Carl,Shetty (ashetty@som.umaryland.edu) - University of Maryland Baltimore