Pluto Bioinformatics

GSE146027: Transcriptome of murine gastric cancer treated with anti-IL-17, PD-1 or CTLA-4 antibodies.

Bulk RNA sequencing

YTN2 and YTN16 cells are chemically induced gastric cancer cell lines. YTN2 is spontaneously regressed in C57BL/6 mice in CD8+ T cell-dependent manner, while YTN16 grows progressively. To investigate the interaction of tumor microenvironment and T cells, bulk RNA-Seq of total tumor RNA were performed in YTN2 and YTN16 gastric tumor-bearing mice. SOURCE: Kazuhiro Kakimi The Tokyo University Hospital