Pluto Bioinformatics

GSE114272: The role of Clk3 in the development of heart hypertrophy

Bulk RNA sequencing

We used RNA-seq technology to characterise the extent of transcriptional response to transverse aortic compression (TAC) in mouse models, both in wild type and in Clk3-knocked down animals. We thereby provide an extensive characterization of the changes occurring at the genome-wide levels, including isoforms switches and splicing patterns. SOURCE: Christophe Chabbert (christophe.chabbert@biol.ethz.ch) - ETH