Pluto Bioinformatics

GSE106709: RNA Sequencing for reprogrammed beta cells

Bulk RNA sequencing

Alpha-cell-derived INS+ cells (yellow cells) were isolated 1 month after AAV-PM (adeno-associated virus carrying pdx1 and mafA under the CMV promoter) infusion from ALX-treated GCG-Cre; R26RTomato; MIP-GFP mice, based on expression of tomato red (alpha-cell lineage) and GFP by flow cytometry. Sorted normal GFP+ beta cells and normal TOM+ alpha cells from GCG-Cre; R26RTomato; MIP-GFP mice without any treatment were used as controls. SOURCE: Xiangwei Xiao (xiangwei.xiao@chp.edu) - Children's Hospital of Pittsburgh

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