Pluto Bioinformatics

GSE55275: Activin A and BMP4 Modulation of Wnt/-catenin Signaling Directs Fate Specification of Mesoderm Derivatives from Human Embryonic Stem Cells

Bulk RNA sequencing

We report the derivation of 2 different methods of generating cardiac myocytes from human ESCs. The traditional route is via cardiac progenitor cells and the second, new approach is through re-directing hemogenic endothelium into the cardiac lineage using inhibition of Wnt/b-catenin signaling SOURCE: Chuck Murry (murry@u.washington.edu) - University of Washington