Pluto Bioinformatics

GSE69476: mRNA sequencing of the global effect of SOX2 on gene expression in hESC and hESC derived NPCs.

Bulk RNA sequencing

Global transcriptome analysis reveals that SOX2 regulates a common group safeguarding stem cell identity in hESCs and hNPCs, and also distinct functional groups regulating diverse cell type dependent developmental processes in hESCs and hNPCs, sheding light on the mechanism underlying SOX2's dynamic function in the two related stem cell types. SOURCE: Ying Jin (yjin@sibs.ac.cn) - Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences