Pluto Bioinformatics

GSE134864: H2BG53D mutation in PDAC

Bulk RNA sequencing

Study was conducted to understand the effect of the cancer associated H2BG53D mutation in PDAC. Using CRISPR/Cas9 Knock-in cell lines expressing FLAG-tagged WT and G53D mutant H2B, we conducted gene expression profilling experiments and studied the effect of the H2BG53D mutation on transcription and PDAC development. SOURCE: Ming,Kui,Chan (ming.chan@cityu.edu.hk) - City University of Hong Kong