Pluto Bioinformatics

GSE133922: Global transcriptomic profiling of the bone marrow stromal microenvironment during postnatal development, aging, and inflammation

Bulk RNA sequencing

RNA-sequencing of a longitudinal comparison of four principal mesenchymal and endothelial stromal cell types (CXCL12-abundant reticular cells, PDGFR-+ Sca-1+, sinusoidal and arterial endothelial cells), isolated from early postnatal, adult and aged mice. Additional transcriptional profiling of the response of CXCL12-abundant reticular cells and sinusoidal endothelial cells to infection-mimicking agents. SOURCE: Elena Piñeiro-Yáñez Spanish National Cancer Research Centre (CNIO)