Pluto Bioinformatics

GSE92301: Gene expression profile of hedgehog-responsive stromal cells in mouse PB-MYC prostate tumor and normal prostate

Bulk RNA sequencing

We report the application of RNA-sequencing for high-throughput profiling of gene expression in hedgehog-responsive stromal cells in normal mouse prostate and mouse prostate tumors. By using the Gli1-GFP knock-in reporter mouse line, we isolated the subset of mouse prostate stromal cells undergoing hedgehog signaling to compare the transcriptomes between PB-MYC prostate tumor and normal prostate in mice at the age of about 45 weeks. SOURCE: Zhaohui Yang (zhy2003@med.cornell.edu) - Memorial Sloan Kettering Cancer Center