Pluto Bioinformatics

GSE103923: RNA sequencing of Foxd1Cre;Smo(flox/-) mutant kidneys

Bulk RNA sequencing

Purpose: To analyze the mRNA content of Foxd1Cre;Smo(flox/-) mutant kidneys.; Methods: We collected E13.5 wildtype and Foxd1Cre;Smo(flox/-) mutant kidneys and isolated RNA to do RNA-Seq.; Results: Identified differentially expressed transcripts in Foxd1Cre;Smo(flox/-) mutant kidneys compared to wildtype controls.; Conclusions: Our work provides novel insight into how Hedgehog signaling from stromal cells influences renal development. SOURCE: Norman,D,Rosenblum ( - The Hospital for Sick Children

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