Pluto Bioinformatics

GSE143241: Context-dependent IL-1 mRNA-destabilization by TTP prevents dysregulation of immune homeostasis

Bulk RNA sequencing

We report that TTP exhibits context-dependent target destabilisation and that such context-defined mRNA decay is essential for maintaining steady state IL-1 levels in the physiological range SOURCE: Pavel Kovarik (pavel.kovarik@univie.ac.at) - University of Vienna