Pluto Bioinformatics

GSE86316: Messenger RNA expression after silencing or inhibition of MEN1in MCF-7 breast cancer cells

Bulk RNA sequencing

We performed RNA-seq in MCF-7 cells after silencing of MEN1 using small hairpin RNA's directed at the MEN1 mRNA or chemical inhibition of the MEN1 gene product, menin. We demonstrate that a selected group of transcripts is affected by reduced menin function. SOURCE: Koen,M.A.,Dreijerink (koendreijerink@yahoo.com) - Dana-Farber Cancer Institute