Pluto Bioinformatics

GSE143621: Global assessment of integrated stress response in CF patients lung explants and organoids

Bulk RNA sequencing

Freshly acquired lung tissue from CF patients with advanced disease and prolonged exposure to pathogenic microorganisms display a clear molecular signature of activated unfolded protein response (UPR) and chronic inflammation. SOURCE: Zoya Ignatova (zoya.ignatova@chemie.uni-hamburg.de) - Universitaet Hamburg