Pluto Bioinformatics

GSE111416: RNAseq of germinal center B cells from Blimp-1-GFP reporter mice

Bulk RNA sequencing

RNAseq of germinal center B cells with different Blimp-1-GFP reporter level. Sorted germinal center populations were defined by their expression of Blimp-1-GFP reporter and the cell surface marker CD138 before they were further split into dark zone or light zone / dark zone like or light zone like cells based on their expression of the surface marker CXCR4 and CD83.; We used RNAseq to find genes differentially regulated in various Blimp-1-GFP expressing germinal center populations from the spleen at day 10 after intraperitoneal immunisation with sheep red blood cells. SOURCE: Daniel RadtkeOliver Bannard Laboratory Weatheral Institute of Molecular Medicine