Pluto Bioinformatics

GSE72568: Follicular Helper T Cells Progressively Differentiate to Regulate the Germinal Center Response

Bulk RNA sequencing

Purpose: To compare the transcriptomes of IL-21-expressing, IL-21 and IL-4-expressing, and IL-4 expressing follicular helper T (Tfh) cells and Th2 cells in the spleen at 8 days following helminth infection Methods: Cell sorting of the populations was done for CD4+B220-CD44hiCXCR5hiPD-1hi cells of the various types, followed by mRNA purification. SOURCE: Edward,Isaac,Herman (edward.herman@yale.edu) - Yale University

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