Pluto Bioinformatics

GSE135960: CDK12 inhibition in Hep3B, Huh7 and SNU449 cells

Bulk RNA sequencing

Purpose: to analyze gene expression in THZ531 treated liver cancer cells. Methods: Hep3B and Huh7 cells are treated with THZ531 for 24 hours. SNU449 cells are treated with THZ531 for 48 hours. For RNA sequencing, the library was prepared using TruSeq RNA sample prep kit according to the manufacturers protocol (Illumina). Gene set enrichment analysis was performed using gene set enrichment analysis software. SOURCE: Cun Wang (c.wang@nki.nl) - Rene Bernards The Netherlands Cancer Institute

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