Pluto Bioinformatics

GSE88779: Mouse Pancreatic Islet Maturation Time Series

Bulk RNA sequencing

Beta cells are the sole source of insulin in our body, yet we do not understand how they mature into fully functional, glucose-responsive beta cells. We generated transcriptomes of FACS-purified beta cells using the Ins1-H2b-mCherry reporter line (Jax # 028589) at different peri- and postnatal maturation stages. This enables a systematic comparison across thousands of genes as beta cells mature. SOURCE: Mark,O.,Huising (mhuising@ucdavis.edu) - Huising lab University of California, Davis