Pluto Bioinformatics

GSE137321: c-Maf regulates the plasticity of group 3 innate lymphoid cells by restraining the type 1 program [RNA-seq]

Bulk RNA sequencing

The transcription factor c-Maf is an essential regulator of group 3 ILC homeostasis and effector plasticity. c-Maf limits acquisition of the type 1 program and conversion to the ILC1 fate through restraint of T-bet expression and function. SOURCE: Maria Ciofani (maria.ciofani@duke.edu) - Duke University Medical Center