Pluto Bioinformatics

The Poly(C) binding protein Pcbp2, and its retrotransposed derivative Pcbp1, are independently essential to mouse development (GSE72491)

Bulk RNA sequencing

Pcbp1 and Pcbp2 are essential for mouse embryonic development and post-natal growth, Pcpb2 role in hematopoiesis, and Pcbp1 has evolved essential functions in the genome. SOURCE: Ian,M,Silverman (iansilv@mail.med.upenn.edu) - Brian D. Gregory Lab University of Pennsylvania