Pluto Bioinformatics

GSE99619: Liver DGE analysis of hemophilia mice (hFIX9-R29X) treated with ASOs inhibiting NMD

Bulk RNA sequencing

To evaluate the impact of ASO-mediated depletion of NMD factor Upf1 and Upf3b on the normal transcriptome, we performed digital gene expression analysison hFIX-R29X mouse liver treated with Upf3b-GalNAc-ASO. SOURCE: Sagar,S,Damle (sdamle@ionisph.com) - Ionis Pharmaceuticals