Pluto Bioinformatics

GSE117012: CD73 knockdown effect in pancreatic cancer cell lines

Bulk RNA sequencing

Recent studies have shown that non-enzymatic function of CD73 play a key role in tumor progression, but this function of CD73 in pancreatic cancer cells has not been studied. In the present study, PANC-1 cell lines were transfected with CD73 siRNA, and proliferation ability and cell cycle was significantly inhibited. However, little is known about the mechanisms involved in CD73 regulation in tumors. SOURCE: Liangjing Zhou (124929619@qq.com) - Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China

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