Pluto Bioinformatics

GSE109231: RNA-Seq in human T-cell lymphoblastic lymphoma samples and control thymuses

Bulk RNA sequencing

Precursor T-cell lymphoblastic neoplasms are aggressive haematological neoplasm that most often manifest with extensive marrow and blood affectation (T-cell acute lymphoblastic leukaemia or T-ALL) or less commonly as a thymic mass with limited bone marrow infiltration (T-cell lymphoblastic lymphoma or T-LBL). Here we show data from RNA-Seq in a sample series of T-LBL from Spanish patients.The goal was to determine the levels of expression of coding genes and microRNAs, and to identify all genetic variants including SNVs, indels, and fusion transcripts. SOURCE: Osvaldo Graña (ograna@cnio.es) - Bioinformatics Unit CNIO