Pluto Bioinformatics

GSE138370: Changes in calcium homeostasis and gene expression implicated in epilepsy in hippocampi of mice overexpressing ORAI1

Bulk RNA sequencing

We showed that the overexpression of ORAI1 in the neurons of murine brain leads to spontaneous occurrence of seizure-like events in aged animals by altering Ca2+ response. SOURCE: Bartosz Wojtas (bartoszwojtas83@gmail.com) - Nencki Institute of Experimental Biology