The cellular response to replication stress requires the DNA-damage responsive kinase ATM and its co-factor ATMIN, however the roles of this signaling pathway following replication stress are unclear. RNA-seq and subsequent differential expression analyses were utilized to identify the functions of ATM and ATMIN in response to replication stress induced by Aphidcolin (APH). SOURCE: Abdelghani Mazouzi (abdelghani_mazouzi@hotmail.fr) - Joanna Loizou lab CeMM

Pluto Bioinformatics

GSE72275: Mapping Replication Stress-Dependent Transcriptional Events Dependent on ATM or ATMIN by RNA-seq