Pluto Bioinformatics

GSE123674: Axl targeting in experimental unilateral ureteral obstruction

Bulk RNA sequencing

We investigated if Axl receptor tyrosine kinase was up-regulated in unilateral ureteral obstruction (UUO) and if blocking of Axl by a small molecule called BGB324 (also called Bemcentinib) reduces fibrosis development in the ligated kidney as compared to treatment with its vehicle alone. SOURCE: Tomasz Stokowy (tomasz.stokowy@k2.uib.no) - Genomics Core Facility University of Bergen