Pluto Bioinformatics

GSE92456: Transcriptome analysis of dominant-negative Brd4 mutants identifies Brd4-specific target genes of BET inhibitor JQ1

Bulk RNA sequencing

We analyzed anti-proliferative dominant-negative Brd4 mutants that compete with the function of distinct Brd4 domains. We used these Brd4 mutants to compare the Brd4-specific transcriptome with the transcriptome of JQ1 treated cells. SOURCE: Caroline Friedel Ludwig-Maximilians-Universität München