Purpose: We performed RNA-Seq on 2.5dpc mouse hypothalamus, pituitary, ovary and uterus of 8-10 week old littermate female control and Kdm4a knockout mice. Upon observing for the extent of altered genes of physiological relevance to observed female infertility phenotype, this would help us narrow down the most relevant tissue to perform genome wide ChipSeq binding profiles for Kdm4a, H3K4me3 and H3K9me3. This dataset would present likely target genes under direct control of Kdm4a. SOURCE: Aditya Sankar (aditya.sankar@bric.ku.dk) - Helin University of Copenhagen

Pluto Bioinformatics

GSE96685: 2.5 dpc female HPG axis RNASeq of Kdm4a wildtype and knockout mice