Pluto Bioinformatics

GSE154173: Heat shock protein gp96 induces Foxp3 expression in Regulatory T Cells via interaction with TLRs for treatment of Auto-immune Diseases [FFoxp3-GFP-hCre]

Bulk RNA sequencing

Upregulate and stabilize Foxp3 expression in Treg are essential for manipulating Treg cell function and immune homeostasis. Here, we examined the potential role and mechanism of gp96 protein in regulating FoxP3 transcription and Treg activation in vivo. SOURCE: Songdong Meng (mengsd@im.ac.cn) - nstitute Of Microbiology Chinese Academy of Sciences