Pluto Bioinformatics

GSE154133: Effects of PAK4 knockdown on gene expression in glioblastoma-associated endothelial cells

Bulk RNA sequencing

PAK4 was knocked down in human glioblastoma (GBM)-associated endothelial cells (ECs) using CRISPR-Cas9/gRNA. RNA was isolated and analyzed by RNAseq. The effects of PAK4 knockout on gene expression were determined. SOURCE: Yi Fan (Yi.Fan@pennmedicine.upenn.edu) - Fan Lab University of Pennsylvania

Dive into this experiment on Pluto.bio! Explore a myriad of analyses and visualizations, from differential expression and PCA to UMAP, t-SNE, gene set enrichment, and more. Discover insights through summary reports, coverage maps, clustering, and beyond. Also access to over 14,000 published experiments. Learn more