Pluto Bioinformatics

GSE108946: Transcriptome time course of mouse acute myeloid leukemia cells upon PU.1 restoration and knockdown

Bulk RNA sequencing

We have utilized advanced RNAi technology to dynamically restore and subsequently knock down endogenous PU.1 expression in p53-deficient AML cells, which respectively causes differentiation and de-differentiation SOURCE: Ruijie Liu (cliu@wehi.edu.au) - Ritchie lab walter and eliza hall institute of medical research