We described a highly efficient method to establish the immortalized HepLPC cell, these cell lines could efficiently expand and able to readily differentiate back into metabolically functional hepatocytes. To further characterize them, we compare the global expression profiles among immortalized human liver progenitor-like cells (iHepLPCs), hepatocyte-like cells differentiated from iHepLPCs (iHepLPCs-Hep) and 3D cell spheroids of the iHepLPCs-Hep (iHepLPCs-Hep-3D). SOURCE: yan hexin (hexinyw@163.com) -  Renji Hospital Affiliated to Shanghai Jiaotong University School of Medicine

Pluto Bioinformatics

GSE124528: Gene expression analysis of immortalized human liver progenitor-like cells in culture