Pluto Bioinformatics

GSE87694: Olfactory receptor accessory proteins play crucial roles in receptor gene choice

Bulk RNA sequencing

Mice with olfactry accessory protein RTP1 and RTP2 knocked out show severe bias in their olfactory receptor repertoire. Surprisingly, even though RTP1,2(-/-) animals have fewer OSNs, we discovered ~8% of the ORs are expressed in larger numbers than the wild type. SOURCE: Kentaro IKEGAMI (kentaro.ikegami@yohda.net) - Duke University