Pluto Bioinformatics

GSE140742: ASK1 Inhibition Reduces Cell Death and Hepatic Fibrosis in an Nlrp3 Mutant Liver Injury Model

Bulk RNA sequencing

The aim of the current study was to investigate whether pharmacologic inhibition of ASK1 could attenuate hepatic fibrosis driven by inflammasome activation using gain-of-function NOD-like receptor protein 3 (Nlrp3) mutant mice. SOURCE: Li Li (li.li@gilead.com) - Gilead Sciences