Pluto Bioinformatics

GSE145180: RNA-seq of GAP43 overexpressed and control SW620 cancer cells

Bulk RNA sequencing

We found GAP43 was significantly downregulated in colorectal cancer. So we reintroduced GAP43 to colorectal cancer cell line, and investigated the influence to cancer cells. In order to get the transcriptome-wide impact of GAP43 overexpression in colorectal cancer, we made stable transfected GAP43 in SW620 cancer cells, and mRNA-seq were performed (Sequenced with PE150, and 20M reads were generated.) This study provides the DEGs of GAP43 overexpressed and control colorectal cancer cells. SOURCE: Hongjin WU (wuhongjin@hit.edu.cn) - Hangzhou Cancer Hospital