Pluto Bioinformatics

GSE146981: Single cell RNAseq reconstruct normal and IPF lung epithelium

Bulk RNA sequencing

Tissue fibrosis is a common pathological outcome of chronic disease that markedly impairs organ function leading to morbidity and mortality. In the lung, idiopathic pulmonary fibrosis (IPF) is an insidious and fatal interstitial lung disease associated with declining pulmonary function. Single cell RNA sequencing was used to map epithelial cell types of the normal human airway and alveolaor as well as IPF explant tissue. SOURCE: Changfu Yao (changfu.yao@cshs.org) - Stripp Lab cedars-sinai medical center